Ovary steroidogenesis abnormality and ovary dysfunction due to indomethacin.
نویسندگان
چکیده
منابع مشابه
Placental steroidogenesis in pregnant women with polycystic ovary syndrome.
OBJECTIVE To evaluate the placental activity of steroid sulfatase (STS), 3β-hydroxysteroid dehydrogenase type 1 (3β-HSD-1) and P450 aromatase (P450arom) in polycystic ovarian syndrome (PCOS) compared to normal pregnant women. DESIGN Twenty pregnant women with PCOS and 30 control pregnant women who delivered at term were studied. Samples of placental tissue and cord blood were obtained after d...
متن کاملEndometrial abnormality in women with polycystic ovary syndrome.
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy associated with infertility and metabolic disorder in women of reproductive age. Although the clinical and biochemical features are heterogeneous with individuals, the most widely accepted clinical characteristics of PCOS are oligo- or anovulation combined with hyperandrogenism. With the higher rate of implantation failure after...
متن کاملPolycystic ovary syndrome: implications of metabolic dysfunction.
OBJECTIVE To determine the prevalence of metabolic syndrome (MS) and its clinical interrelations in polycystic ovary syndrome (PCOS). METHODS This was a cross-sectional, prospective study with 100 patients with diagnosed PCOS based on the consensus of Rotterdam (2003). We investigated the interrelationships of MS, with intrinsic PCOS data. Dermatological profile was analyzed, in addition to a...
متن کاملHyperandrogenic anovulation (the polycystic ovary syndrome)--back to the ovary?
Hyperandrogenic anovulation is characterized by polycystic appearance of the ovaries, elevated free serum testosterone with decreased concentrations of serum sex hormone binding globulin, an increased ratio of luteinizing hormone to follicle stimulating hormone and varying degrees of insulin resistance. We hypothesize that this is the result of variably increased 'ovarian androgenic insulin res...
متن کاملSteroidogenesis-related gene expression in the rat ovary exposed to melatonin supplementation
OBJECTIVE To analyze steroidogenesis-related gene expression in the rat ovary exposed to melatonin supplementation. METHODS Thirty-two virgin adult female rats were randomized to two groups as follows: the control group GI received vehicle and the experimental group GII received melatonin supplementation (10 µg/night per animal) for 60 consecutive days. After the treatment, animals were anest...
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ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 1987
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.18.79